This mission is identical, mission tasks and objectives, to the original version of Cloaked in Silence. The Extreme set of rules is pretty self-explanatory, as it basically means that enemies will deal more damage to you, meaning that direct combat is not something you want to do. You have full use of your tools and Buddies in these missions (no Buddy for this one, actually), except for the Chicken Hat and Reflex Mode.

The same strategy that you might have used to cheese this battle (dropping a supply drop on her) for the normal version of the mission won’t work as well here, as Quiet will simply move out of the way whenever you try to drop one on her. The tough part about this mission is that one shot from Quiet will usually kill you, unless you’re using another character with Tough Guy and have the upper tiers of the Battle Armor equipped.

You can resort to doing a sniper battle, peeking out to bait Quiet into taking a shot, then using that short window where she is reloading to hit her. However, if you have a tank, you can drop one into the battle area and use that to take her out, which is an easier way to achieve the S-Rank.